Spearman rank correlations concerning log Ki for binding in vitro As well as in vivo log ED50 parameters of the triad check (A–C). Spearman rank correlations in between log EC50 for efficacy in vitro and in vivo log ED50 parameters from the triad check (E–F). Chromatographic peaks of prospective metabolites https://rarechemsonline.org/product/5f-mdmb-2201/