There exists a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to minimize afferent discomfort transmission and deliver analgesia. Hence, medication like clonidine that target alpha-2 receptors can influence the transmission of suffering. Clonidine is dispersed in breast milk; caution https://hughi146ljd5.sasugawiki.com/user