Importantly, these receptors were being observed to are already activated by an array of endogenous opioids at a concentration comparable to that observed for activation and signaling of classical opiate receptors. In turn, these receptors were found to possess scavenging activity, binding to and lowering endogenous levels of opiates https://sergioloepc.tribunablog.com/details-fiction-and-does-conolidine-relieve-pain-52775315